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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MET
All Species:
4.55
Human Site:
S1385
Identified Species:
12.5
UniProt:
P08581
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08581
NP_000236.2
1390
155541
S1385
E
V
D
T
R
P
A
S
F
W
E
T
S
_
_
Chimpanzee
Pan troglodytes
Q2QLF1
1390
155551
S1385
E
V
D
T
R
P
A
S
F
W
E
T
S
_
_
Rhesus Macaque
Macaca mulatta
NP_001162100
1381
154449
Dog
Lupus familis
XP_533823
1410
153277
R1399
P
V
H
R
N
T
G
R
L
R
P
F
S
E
P
Cat
Felis silvestris
Mouse
Mus musculus
P16056
1379
153530
Rat
Rattus norvegicus
P97523
1382
153923
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07E01
1382
154611
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
NP_001163830
1425
157559
P1403
S
S
S
L
S
S
D
P
T
T
S
T
S
L
P
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190267
1321
146315
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.1
35.1
N.A.
88.8
87.7
N.A.
77.3
N.A.
N.A.
N.A.
48.4
N.A.
N.A.
N.A.
28.7
Protein Similarity:
100
99.8
98.7
52.2
N.A.
94.4
93.5
N.A.
86.6
N.A.
N.A.
N.A.
66
N.A.
N.A.
N.A.
48.9
P-Site Identity:
100
100
0
13.3
N.A.
0
0
N.A.
0
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
0
13.3
N.A.
0
0
N.A.
0
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
23
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
23
0
0
0
12
0
0
0
0
0
0
0
0
% D
% Glu:
23
0
0
0
0
0
0
0
0
0
23
0
0
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
23
0
0
12
0
0
0
% F
% Gly:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% G
% His:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
12
0
0
0
0
12
0
0
0
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
0
0
0
0
23
0
12
0
0
12
0
0
0
23
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
12
23
0
0
12
0
12
0
0
0
0
0
% R
% Ser:
12
12
12
0
12
12
0
23
0
0
12
0
45
0
0
% S
% Thr:
0
0
0
23
0
12
0
0
12
12
0
34
0
0
0
% T
% Val:
0
34
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
23
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
23
23
% _